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]] The Conduit Artery Function Evaluation (CAFE) study, a substudy of the ground-breaking ASCOT study, showed that the treatment combinations used had different effects on central systolic aortic blood pressure, with a significant advantage for the perindopril and amlodipine combination.
Williams is the principal investigator for the Differential Impact--Principal Results of the Conduit Artery Function Evaluation (CAFE) study in ASCOT.
Differential Impact of Blood Pressure-Lowering Drugs on Central Arterial Pressure influences Clinical Outcomes - Principal Results of the Conduit Artery Function Evaluation (CAFE) Study in ASCOT.