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The research team, led by Gerold Bepler, MD, PhD, Professor of Medicine and Oncology at Moffitt, used the HistoRx PM-2000(TM) instrument and AQUA(R) technology to measure expression levels of RRM1 (the regulatory subunit of ribonucleotide reductase) and ERCC1 (excision repair cross complementation group 1 protein) in tumors from 187 patients with early-stage non-small-cell lung cancer.