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19, 2013 /PRNewswire/ -- Edison Pharmaceuticals today announced the initiation of a phase 2 clinical trial entitled, "Double-Blind, Placebo-Controlled Clinical Trial of EPI-743 in Patients with Cobalamin C Defect.
Furthermore, neurological rather than hematologic symptoms may be the only clinical indications (2), and a relationship between low concentrations of cobalamin and neurological symptoms has been reported (3, 4).
OBJECTIVE: To evaluate the use of oral cyanocobalamin therapy in the treatment of cobalamin (vitamin B(12))-deficient anemia.
The delivery of cobalamin from food to tissues involves first the binding of cobalamin from the diet to the salivary protein haptocorin.
Effective treatment of cobalamin deficiency with oral cobalamin (Blood 1998;92:1191-8).
These partnerships have produced products such as methylcobalamin (vitamin B12), also called cobalamin, which helps maintain healthy nerve cells and red blood cells; Shugr, a zero-calorie, low glycemic sweetener that tastes and measures like table sugar; EstraFlex CMO, an ingredient for joint health, assisting in flexibility and mobility; and Stevia, a new natural sweetening agent that can be widely applied to food, drinks, medicine and daily chemicals.
The grown bacteria are allowed to metabolize a mixed gas, prepared by adding hydrogen to at least one of coal gas and biogas, into methane and at the same time, cobalamin contained in the fermented liquor is recovered as an extracellular product in the form of cyanocobalamin by using potassium cyanide to thereby produce vitamin B12 efficiently in a high content and high yield.
This hybrid method allows scientists to quickly detect and measure levels of specific individual cobalamins in food and supplement samples.