What does CDI stand for?

Interrater reliability of the Clinical Dementia Rating in a multicenter trial.

In a secondary cognitive measure, the Clinical Dementia Rating sum of boxes, both groups lost 2.

In unadjusted analyses, GBE neither altered the risk of progression from normal to Clinical Dementia Rating (CDR) = 0.

The intervention group showed significantly better delayed recall, lower scores on the Clinical Dementia Rating, and better scores on the Alzheimer's Disease Assessment Scale-Cognitive subscale at 6-, 12-, and 18-month assessments, the investigators said.

The secondary outcome was global function as assessed with the Clinical Dementia Rating Scale; safety and tolerability of omega 3 fatty acid supplementation; and blood pressure determinations.

Both men and women aged 85 years and older who can identify a collateral informant who has frequent contact with the subject, have normal memory function defined by an education-adjusted score on the Logical Memory Subscale of the Wechsler Memory Scale Revised, have a Clinical Dementia Rating of zero, and a Mini-Mental State Examination Score [greater than]23 are eligible.

The MMSE and Clinical Dementia Rating Scale (CDR) were used as global measures of the stage of Alzheimer disease.

In non-carriers of the Apolipoprotein E4 (ApoE4) allele, estimated in the literature to be from 40 to 70 percent of the Alzheimer's disease population, post-hoc analyses showed statistically significant and clinically meaningful benefits associated with bapineuzumab treatment on several key efficacy endpoints, including the Alzheimer's Disease Assessment Scale (ADAS-cog), the Neuropsychological Test Battery (NTB), the Mini Mental State Examination (MMSE) and the Clinical Dementia Rating - Sum of Boxes (CDR-SB).