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The method is useful for the treatment of congenital or acquired aplastic or hypoplastic anemia associated with chronic renal failure, end-stage renal disease, renal transplantation, cancer, AIDS, chemotherapy, radiotherapy, bone marrow transplantation and chronic diseases.
The patient was diagnosed with chronic renal failure secondary to hypertensive nephrosclerosis and prescribed hemodialysis and blood transfusions.
Hyperphosphatemia, which is a common symptom of patients in the terminal or advanced stages of chronic renal failure, induces severe conditions like cardiovascular episodes and bone disease.
There is extra stress on the surviving cells and this leads to more deterioration of the kidneys, called chronic renal failure (CRF).
Due to the longer serum half-life, Aranesp should be administered to chronic renal failure patients less frequently than Epoetin alfa, thus, simplifying anemia management for patients and healthcare providers.
In the study, published in the 20 September 2000 issue of JAMA, the researchers stated that although the amounts of lead found were small, they could pose a potential risk to certain people who take larger-than-usual doses of calcium, such as those with chronic renal failure.
The drug, NESP, already has been submitted for approval by the Food and Drug Administration for use in chronic renal failure patients.
That's why a middle-age person with chronic renal failure has less than a 50-50 chance of living more than 5 years on dialysis.