What does CMPD stand for?

In this report, we will contrast a patient with idiopathic hypereosinophilia with a patient presenting with hypereosinophilia involving a chronic myeloproliferative disorder.

To make a definitive diagnosis of Gaucher disease, assays for acid [Beta]-glucosidase activity in white blood cells or fibroblasts must be performed, because Gaucher-like cells may be found in patients with other conditions, such as chronic myeloproliferative disorders, chronic dyserythropoietic anemias, thalassemia, Shwachman syndrome (overloading of normal enzymatic capacity to process normal cell breakdown), or other malignant conditions.

These data not only provide support for our active Phase 2 trials of obatoclax in small cell lung cancer and adult myeloid leukemia, but also introduce an opportunity for our accelerated development of obatoclax for the treatment of systemic mastocytosis, a rare and progressive chronic myeloproliferative disorder for which there are very limited treatment options.