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What does CDCA stand for?

Chenodeoxycholic Acid


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Samples in periodicals archive:
Medicines called chenodeoxycholic acids (CDCA) or ursodeoxycholic acid (UDCA, ursodiol) may be given to dissolve the stones.
1) Chenodeoxycholic acid is unconjugated and is active at a neutral pH but not at an acid pH of 2.
The farnesoid X receptor (FXR) is a receptor for bile acids such as chenodeoxycholic acid (CDCA), deoxycholic acid, cholic acid, and their conjugates.
Short of surgery, the only gallstone therapy currently approved in the United States is treatment with chenodeoxycholic acid.
Oral administration of UDCA in humans leads to a significant change in the relative proportions of the biliary and serum bile acids, such that UDCA becomes the major bile constituent (about 50 percent when a 13-15 mg/kg/day dose is given) and naturally replaces cholic and chenodeoxycholic acids.
Am J Cardiol 76: 21-28 Danzinger RG, Hofmann AF, Schoenfield LJ, Thistle JI (1972) Dissolution of cholesterol gallstones by chenodeoxycholic acid.
Lim AG, Ahmed HA, Jazrawi RP, et al: The effect of ursodeoxycholic acid and chenodeoxycholic acid on human hepatocyte and erythrocyte membranes.

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