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Known as base excision repair, it begins with the uracil-N-glycosylase enzyme, which acts to search through dsDNA for any uracil residues.
This process is therefore called base excision repair.
Because base excision repair (BER) is the predominant pathway involved in repairing oxidative damage, Barry et al.
MUTYH-associated polyposis (MAP) is an autosomal recessive syndrome associated with biallelic germline mutations in the base excision repair gene MUTYH (OMIM #608456) (1).
Recent advances indicate DNA base excision repair (BER) protein, i.
Base excision repair (BER) pathway is the most pro-active DNA repair pathway that corrects DNA modifications which arise either spontaneously or from attack by reactive chemicals i.
TRC102 is a small molecule inhibitor of base excision repair that improves the therapeutic index of commonly used antimetabolite and alkylating agent chemotherapies.
Molecular mechanism of PCNA-dependent base excision repair.