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This is diagnosed by performing a blood test for two antibodies; the anticardiolipin antibody and the lupus anticoagulant.
Elevated serum IgA anticardiolipin antibody levels in adult Henoch-Schonlein purpura.
The study examined the association between adverse pregnancy outcome and the presence of three different aPLs: lupus anticoagulant [LAC], anticardiolipin antibody [aCL] and antibody to beta 2 glycoprotein I.
These studies were of small populations, however, and did not follow the current strict guidelines for classifying anticardiolipin antibody and lupus anticoagulant concentrations as positive (27).
Introduction In this report, we present an interesting case of a combined heterozygote factor V Leiden mutation and anticardiolipin antibody positivity in a young patient with spontaneous deep vein thrombosis, which emphasizes importance of thrombophilia.
Their study results were found to mirror the results noted in the 2003 College of American Pathologists ACL-B survey for anticardiolipin antibody proficiency testing where an 80% consensus was reached for only five of the nine (55%) samples distributed for testing.
Anticardiolipin antibody of IgG or IgM isotype present in medium or high titer in serum or plasma on two occasions at least 12 weeks apart.
2) Of these, RF was found in 38 to 71% of patients, (2,4,5) antinuclear antibody in 10 to 41%, (2,3,4,5) antismooth muscle antibody in 9 to 22%, antithyroglobulin antibody in 7 to 14%, anti-LKM1 antibody in 5%, and anticardiolipin antibody in up to 44%.