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16) Iron deficiency anemia and anemia of chronic disease are the main types of anemia in IBD.
Anemia of chronic disease (ACD), also known as anemia of inflammation, is a hypoproliferative anemia that develops in response to systemic illness or inflammation such as infection, cancer, and autoimmune conditions.
A normocytic, normochromic anemia of chronic disease was noted with a hemoglobin of 10 g/dL.
Anemia of chronic disease and hyperbilirubinemia can decrease the specificity of an iron deficiency diagnosis based on hematofluorometry-determined increases in the ratio of ZnPPIX to heme.
Laboratory data was significant for an anemia of chronic disease.
Laboratory tests demonstrated anemia of chronic disease diagnosed by a hematocrit of 25% associated with a low reticulocyte production index, high serum ferritin, and an elevated erythrocyte sedimentation rate (91 mm/hr), with polyclonal hypergammaglobulinemia and hypoalbuminemia on serum protein electrophoresis.
com About NOX-H94 & Anemia of Chronic Disease NOX-H94 is a Spiegelmer([R]) compound targeting the iron-regulating protein hepcidin.
Together, the Access Soluble Transferrin Receptor (sTfR) Assay and the sTfR/log ferritin index (sTfR Index) act as an aid in the diagnosis of iron-deficiency anemia (IDA) and the differential diagnosis of IDA and anemia of chronic disease (ACD).