What does APP stand for?

Amyloid Precursor Protein (neurology)

This definition appears very rarely and is found in the following Acronym Finder categories:

Science, medicine, engineering, etc.

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Samples in periodicals archive:

Byline: ANI Washington, Oct 19 (ANI): The amyloid precursor protein, or APP, associated with the development of Alzheimer's disease, has also been found to play a critical role in brain development, say researchers.

Protein linked to Alzheimer's plays critical role in brain development

42]) in the brain by changing the point at which the enzyme gamma secretase cuts the amyloid precursor protein, shifting the ratio to less of the toxic [AB.

Failed Alzheimer's trials shift focus to prevention

There is compelling evidence that sAPPbeta, the ectodomain of amyloid precursor protein (APP) shed through beta secretase cleavage, is an important component in the pathogenesis of AD," said Joe Bertelsen, neuroscience product manager, Covance.

COVANCE ADDS ALZEIMER'S ASSAY TO PORTFOLIO

Using cultured cells from mice, the scientists showed that the antibodies first bind to the surface of the cells and connect to a protein called amyloid precursor protein (APP), which is already present on the cell surface.

Scientists Raise Hopes For Alzheimer's Vaccine

Other topics of the 12 contributions include signal transduction pathways leading to caveolin tyrosine phosphorylation, lipid rafts in the trafficking of prion protein and amyloid precursor protein, and the role of careolin-1 in tumor cell survival and cancer progression.

Lipid Rafts and Caveolae

Yu and his colleagues discovered that nicastrin binds to several proteins lodged in the cell's membrane, including one called amyloid precursor protein, or APP.

Alzheimer's disease enzyme identified

Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.

Neural protein may stop the progression of Alzheimer disease

PS1 is believed to function as the "gamma secretase" that cleaves amyloid precursor protein to yield beta-Amyloid (A [beta]) peptides.

Refining the kokanee salmon model of vertebrate brain aging and ...