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These mutations reduce the ability of alveolar macrophages to remove used surfactant from the lungs of these children.
When asbestos fibers penetrate and deposit on alveolar surfaces, alveolar macrophages attempt to engulf them and remove them from the site of deposition.
We used all three batches in the Western analyses of alveolar macrophages (autophagy markers and MAP kinases).
To exert these functions, the alveolar macrophages interact with molecules (i.
Alveolar macrophages, a type of white blood cell residing in our lungs, initially recognize the bacteria and engulf them.
The 54 papers discuss such aspects as the proteomic dissection of viral pathogenesis, identifying genes involved in tick infestation in cows, the dynamic differential regulation of innate immune transcripts during the infection of alveolar macrophages by the porcine reproductive and respiratory syndrome virus, and using RNAi and transgenics to develop viral disease resistant livestock.
Alveolar macrophages were obtained (12) and their suspension was made in RPMI 1640 (High Media Laboratories Ltd.
The initial underlying pathologic process in the lung from amiodarone toxicity is postulated to be a drug-induced phospholipidosis, (9) and the mechanism by which phospholipids accumulate in the cell is believed to be by inhibition of intracellular phospholipase when the drug and its metabolites are trapped in alveolar macrophages and type II pneumocyte lysosomes.