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Bream will work with University of Nebraska scientists to further analyze various compounds for their affinity to alpha-2 adrenergic receptors and subreceptors that might enhance efficacy or reduce side effects of current alpha-2 compounds.
Alpha-2 adrenergic receptors (ARs) are important regulators of many physiological processes (1).
The alpha-2 adrenergic receptors in particular have been implicated in a wide variety of medical conditions, including hypertension, ADHD, menopausal flushing, migraine, sleep disturbances, aggression, pain and addiction.