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Samples in periodicals archive:
A year ago, Ziouzenkova's lab identified the one of these enzymes that relates to fat accumulation: Aldehyde Dehydrogenase 1, or Aldh1a1.
The company's clinical programs include: Palifosfamide (Zymafos(R) or ZIO-201) is a novel DNA cross-linker that in preclinical study has been shown to bypass resistance mediated by aldehyde dehydrogenase (ALDH), in addition to conferring a favorable toxicity profile compared to other in-class agents.
Aldehyde dehydrogenase 2 (ALDH2) is a key enzyme in ethanol metabolism.
Aof people from Asia lack the enzyme aldehyde dehydrogenase.
The article will focus on recent data identifying a phenomenon called ethanol-induced preconditioning as well as on an unexpected player in alcohol-induced cardioprotection, the alcohol-metabolizing mitochondrial enzyme aldehyde dehydrogenase 2 (ALDH2).
Acetaldehyde, the first and most toxic metabolite of alcohol, is broken down by alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH).
Raptor currently has product candidates in clinical development designed to potentially treat nephropathic cystinosis, non-alcoholic steatohepatitis ("NASH"), Huntington's Disease ("HD"), aldehyde dehydrogenase ("ALDH2") deficiency, and a non-opioid solution designed to potentially treat chronic pain.
Raptor currently has product candidates in clinical development to treat nephropathic cystinosis, non-alcoholic steatohepatitis ("NASH"), Huntington's Disease ("HD"), and aldehyde dehydrogenase ("ALDH2") deficiency.