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Limited options exist for both the first- and second-line treatment of advanced bladder cancer and there continues to be a high unmet need for additional therapeutic options for this patient population.
Lead researcher Dr Thomas Powles, of Queen Mary University of London, said: "This is a hugely exciting step in the search for alternative and effective advanced bladder cancer treatment.
Alex Yeung, the company s chief executive, commented the money also allows Cold Genesys to immediately develop other treatment options in advanced bladder cancer as well as in other solid tumors.
Patients with advanced bladder cancer that are removed surgically might need additional therapy to prevent recurrence in certain situations, suggests a study in European Urology.
8220;IMRT also has demonstrated efficacy when used to treat pain in advanced bladder cancer.
Neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and cisplatin followed by radical cystectomy improves survival among patients with locally advanced bladder cancer when compared with surgery alone.
More than half of the patients with advanced bladder cancer experience recurrences.
Current understanding of the biology of advanced bladder cancer.