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What does ACAT stand for?

ACAT stands for Acetyl CoA (Coenzyme A): Acetyltransferase

This definition appears very rarely and is found in the following Acronym Finder categories:

  • Science, medicine, engineering, etc.

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We have 94 other meanings of ACAT in our Acronym Attic

Samples in periodicals archive:

SIRT1 and SIRT6), HDACs, and HATs, which require acetyl CoA from the TCA cycle; nutrient sensing through the AMPK and mTOR signaling pathways; DDR mediated by PARP, ATM, SIRT1, and AMPK; and redox signaling through overlapping pathways mediated by ATM/Chk2, p53, Hif1-[alpha], ERK, and NF[kappa]B.
In cells with mitochondria that contain enzymes capable of transforming acetate to acetyl CoA, such as heart, skeletal muscle, and brain, the acetate is eventually metabolized to C[O.
The recent observation showing acetylation of proteins by calreticulin (an endoplasmic reticulum resident protein) with a high efficiency when polyphenolic acetates are the acetyl group donating molecules and acetyl CoA as weak substrate extends the realm of protein acetylation beyond HAT/HDAC combination.
These include acetyl CoA carboxylase, the rate limiting enzyme that initiates fatty acid synthesis.
One possible hint is that the statins block an early step in the enzymatic pathway that eventually turns acetyl CoA into cholesterol, while the nitrogen-containing bisphosphonates--alendronate and risedronate--block a step that occurs later in this pathway.